Do discuss this with your doctor before taking Multibionta as it can also disturb your stomach if you take it on an empty stomach. Pregnancy Category A. Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters). The metabolic clearance rate was 23.5±4.34 ml/min in healthy male volunteers and 10.1±1.35 ml/min in male patients with uraemia . In the pediatric patients undergoing peritoneal dialysis receiving dose of 10.2 ng/kg (SD 5.5 ng/kg) for 2 months, the clearance rate was 15.3 mL/hr/kg .

anemia is known to be associated with an increased incidence of stomach carcinoma, however, this malignancy has been attributed to the underlying cause of pernicious anemia and has not been found to be related to treatment with vitamin B12 . Cyanocobalamin corrects vitamin B12 deficiency and improves the symptoms and laboratory abnormalities associated with pernicious anemia (megaloblastic indices, gastrointestinal lesions, and neurologic damage). This drug aids in growth, cell reproduction, hematopoiesis, nucleoprotein, and myelin synthesis. It also plays an important role in fat metabolism, carbohydrate metabolism, as well as protein synthesis. Cells that undergo rapid division (for example, epithelial cells, bone marrow, and myeloid cells) have a high demand for vitamin B12 . Absorption reduced by antibiotics, aminosalicylic acid, anticonvulsants, biguanides, cholestyramine, cimetidine, colchicine, K salts, methyldopa. This drug is partially excreted in the urine . According to a clinical study, approximately 3-8 mcg of vitamin B12 is secreted into the gastrointestinal tract daily via the bile. In patients with adequate levels of intrinsic factor, all except approximately 1 mcg is reabsorbed. When vitamin B12 is administered in higher doses that saturate the binding capacity of plasma proteins and the liver, the unbound vitamin B12 is eliminated rapidly in the urine. The body storage of vitamin B12 is dose-dependent .

The Multibionta price is 4.90 per capsule in Pakistan. What Medicines are Available as Alternatives to Multibionta in Pakistan?

Unlike ordinary multivitamins, Multibionta contains TriBion Harmonis?, a unique blend of natural probiotic cultures which help to maintain natural balance. This advance in nutrition supports the immune and digestive systems to help you cope with stressful days when you don't get all the nutrients you need. For vitamin B6 deficiency: In most adults, the typical dose is 2.5-25 mg daily for three weeks then 1.5-2.5 mg per day thereafter. In women taking birth control pills, the dose is 25-30 mg per day. The drug is safe in normal doses in pregnant women, but a daily intake of 5 gm or more is reported to have caused abortion. The drug may be taken safely during lactation. Useful interactions:Ascorbic acid increases the apparent half-life of paracetamol and enhances iron absorption from the gastrointestinal tract. Before takingpyridoxine, tell your doctor orpharmacistif you are allergic to it; or if you have any otherallergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.For preventing macular degeneration: 50 mg of vitamin B6 in the form of pyridoxine has been used daily in combination with 1000 mcg of vitamin B12 (cyanocobalamin) 1000 mcg and 2500 mcg of folic acid for about 7 years. To help your doctor and pharmacist give you the best care, be sure to tell your doctor and pharmacist about all the products you use (includingprescription drugs, nonprescription drugs, and herbal products) before starting treatment with this product. While using this product, do not start, stop, or change the dosage of any other medicines you are using without your doctor's approval. There are specific recommended levels for most vitamins and minerals therefore. It is important to be aware of how much of each vitamin and/or mineral is present in a specific food supplement as this may varr from brand to brand. Adhere to the advice given by the healthcare practitioner.

Make sure to take medical care if you encounter any of these side effects.If you have symptoms of high blood pressure then your doctor might prescribe you Zestril tablets. What are the Warning and Risks for Multibionts Capsule? Upon intravenous administration, the volume of distribution of calcitriol was 0.49±0.14 L/kg in healthy male volunteers and 0.27±0.06 l/kg in uraemic male patients participating in a pharmacokinetic study . There is some evidence that calcitriol is transferred into human milk at low levels (ie, 2.2±0.1 pg/mL) in mothers . Calcitriol from maternal circulation may also enter the fetal circulation . For intravenous injection, dilution into a large volume parenteral such as Normal Saline, Water for Injection, or Glucose is recommended to minimize the adverse reactions associated with intravenous injection. Advanced Formula Multibionta 50+ contains a comprehensive and balanced formula to help you stay fit, healthy and full of energy. years ago I used to get terrible cold/flu symptoms this would lay me up for at least 4 dys, since taking multibionta for nearly 4 years I only get very mild colds, im 44 yrs old and the feel good factor and energy i have is superb. I have recommended these to my parents and friends and the results are equally as positive.

Immune Supporting Nutrients. Probiotics. Vitamins A, C, E. Energy Releasing Nutrients. Vitamin B Complex. Iron. Zinc. Nervous System Nutrients. Vitamin B Complex. Antioxidant Protective Nutrients. Vitamins A, C, E. Selenium. Muscle Functioning Nutrients. Vitamin B Complex. Digestive System Nutrients. Probiotics. Protective Probiotic Release System. Gastro Protective Coating 3 Layered Tablet. Other minerals are known as trace elements which are still important, but they are needed in smaller amounts 2. Taking a multivitamin supplement This preparation is used for Pernicious anemia,Vitamin B12 deficiency due to low intake from food,Thyrotoxicosis, Hemorrhage, Malignancy, Liver or kidney disease,Gastric bypass surgery, Total or partial gastrectomy, Gluten enteropathy or sprue, Folic acid deficiency, Macrocytic anaemia In general, folate serum levels below 5 ng/mL indicate folate deficiency, and levels below 2 ng/mL usually result in megaloblastic anemia. Treatment resistance may occur in patients with depressed haematopoiesis, alcoholism, deficiencies of other vitamins. Neonates.